Prediction of early recurrence of pancreatic ductal adenocarcinoma after resection

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Biomarkers as Predictors of Recurrence following Curative Resection for Pancreatic Ductal Adenocarcinoma: A Review

Pancreatic ductal adenocarcinoma (PDA) is the fourth most common cancer causing death in the United States. Early tumor recurrence is an important contributor to the dismal prognosis. The availability of an accurate prognostic biomarker for predicting disease recurrence following curative resection will be beneficial for patient care. Most of the currently studied biomarkers remain in the inves...

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Recurrent pancreatic adenocarcinoma after pancreatic resection.

The patient is a 57-year old Caucasian female who presented with right upper quadrant pain and obstructive jaundice and was diagnosed with resectable pancreatic cancer. She underwent pancreaticoduodenectomy (PD) after preoperative biliary stenting. She subsequently presented to the clinic, where it was noticed that she had an elevated CA 19-9. CT C/A/P revealed multiple new liver lesions.

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The prognostic influence of intrapancreatic tumor location on survival after resection of pancreatic ductal adenocarcinoma

BACKGROUND The prognosis of pancreatic ductal adenocarcinoma (PDAC) is worse when the tumor is located in the pancreatic body or tail, compared to being located in the pancreatic head. However, for localized, resectable tumors survival seems to be at least similar. METHODS We analyzed and compared the outcome after pancreatoduodenectomy (PD) and distal pancreatectomy (DP) for PDAC at our inst...

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Evaluation of survival in patients after pancreatic head resection for ductal adenocarcinoma

BACKGROUND Surgery remains the only curative option for the treatment of pancreatic adenocarcinoma (PDAC). The goal of this study was to investigate the clinical outcome and prognostic factors in patients after resection for ductal adenocarcinoma of the pancreatic head. METHODS The data from 195 patients who underwent pancreatic head resection for PDAC between 1993 and 2011 in our center were...

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Factors affecting long-term survival after surgical resection of pancreatic ductal adenocarcinoma

PURPOSE Some patients who undergo surgical resection of pancreatic cancer survive longer than other patients. The purpose of this study was to identify the factors that affect long-term survival after resection of histopathologically confirmed pancreatic ductal adenocarcinoma. METHODS A single-center, retrospective study was conducted among 164 patients who underwent surgical resection of pan...

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ژورنال

عنوان ژورنال: PLOS ONE

سال: 2021

ISSN: 1932-6203

DOI: 10.1371/journal.pone.0249885